Enterprise Tech Investments & Team Overview | a16z

Michael Truell, CEO of Cursor, sits down with Patrick Collison, CEO of Stripe and an investor in Anysphere, to talk about Collison's history with Smalltalk and Lisp, the MongoDB and Ruby decisions Stripe still lives with...

In this episode from 20VC, Harry Stebbings talks with Anish Acharya, general partner at a16z, about the future of SaaS in an AI world. Anish argues that software is completely oversold and that the general story about vi...

Before an a16z founder event I hosted a few weeks ago, I was telling anyone who would listen that they should really read The Partnership by Charles Ellis, which chronicles Goldman Sachs’s nearly 160 year history. I was...

In this episode, a16z partner Kimberly Tan sits down with Michael Chime, the CEO and co-founder of AI emergency response platform Prepared, for a powerful conversation about how AI is transforming public safety — startin...

In this feed drop from The Six Five Pod, a16z General Partner Martin Casado discusses how AI is changing infrastructure, software, and enterprise purchasing. He explains why current constraints are driven less by technic...

The a16z AI Apps team outlines how they are thinking about the AI application cycle and why they believe it represents the largest and fastest product shift in software to date. The conversation places AI in the context...

Why startups are copying Palantir’s forward-deployed engineer model, where it breaks down, and when high-touch enterprise AI delivery actually scales.

In 2025, we saw the first glimpses of true AI agents. In 2026, every company will be rushing to get them into production, and they’ll need companies like Keycard to manage fleets of agents. In this conversation, a16z Par...

Dylan Field is the co-founder and CEO of Figma, a design software company that went public in July 2025. Founded in 2012, Figma transformed how people design, prototype, and build products together. After a $20 billion a...

AI is becoming the orchestration layer inside the enterprise.

AI is moving from chat to action.

a16z General Partners David Haber, Alex Rampell, and Erik Torenberg discuss why 19 out of 20 AI startups building the same thing will die - and why the survivor might charge $20,000 for what used to cost $20.

Russ Fradin sold his first company for $300M. He’s back in the arena with Larridin, helping companies measure just how successful their AI actually is.

Enterprise sales are evolving fast. Startups are now adapting their GTM playbooks for the AI era: faster pilots, proof-driven demos, and higher trust standards.

Contrary to popular belief, once you’ve sold something, people don’t just rush to pay you. “We have a signed contract, and they’re happy with the service–they should just pay their bills!” Well, the world doesn’t always...

As more software companies launch globally from day one, they’re quickly confronted by a nasty surprise: international tax compliance is one of the hardest parts of scaling a business across borders.

AI-native startups are transforming enterprise software by targeting greenfield companies at formation, winning distribution before incumbents, and redefining business infrastructure across global markets as labor becomes software.

As AI infrastructure providers like OpenAI and Anthropic move up the stack to launch consumer products, startups can build defensible positions by owning exclusive, high-quality data. Companies such as VLex and OpenEvidence show how proprietary, regulated, and dynamic datasets can create durable moats—and where the next “walled gardens” of data may emerge across sectors from law and medicine to climate and culture.

Sam Altman has led OpenAI from its founding as a research nonprofit in 2015 to becoming the most valuable startup in the world ten years later.

Opendoor is trying to make it easier to buy a home. Kaz Nejatian just joined as CEO to help them succeed.

Insurance is a trillion-dollar industry that still runs on PDFs and Excel. It’s not the employees’ fault–the tools they use were primarily built at the dawn of the digital age, or worse yet, were never digitized at all....

A16z Partner Kimberly Tan sat down with the founders of Decagon and Clay at OpenAI’s third annual developer conference, DevDay 2025, to chat about what it actually takes to build and sell AI to the enterprise. They discuss how to make product decisions against a rapidly evolving model landscape, ensure AI pilots are successful, break out in seemingly crowded markets, and more. 

Software has fundamentally changed the way we record, store, and share information. Its next act is to fundamentally change the nature of our economy, capturing trillions of dollars of value in the process.

Explore how startups allocate AI spending across models, infrastructure, creative tools, and vertical applications. See the top 50 AI-native companies driving the next wave of productivity and reshaping the future of work.

Scaling laws took us from GPT-1 to GPT-5 Pro. But in order to crack physics, we’ll need a different approach.

Should the US put a price on H-1B visas, or would that block the flow of new talent? Are AI coding agents actually making teams way more productive, or is it just hype? And in the AI platform shift, will the big winners...

What comes after vibe coding? Maybe vibe researching.

Legal AI is transforming law firms and in-house teams, with impact driven by tools that align with business models, build trust, and automate workflows.

I’ve always believed that “opportunities live between fields of expertise.” That idea has been both an investment philosophy and a metaphor for my career. The most valuable insights often come from combining skills, kno...

OpenAI’s Codex has already shipped hundreds of thousands of pull requests in its first month. But what is it really, and how will coding agents change the future of software?

In the early days of the energy industry, fortunes made in two different way: oil wells and pipelines. AI founders now face the same choice. Go deep into a single workflow or build a pipeline that moves data and automations.

Autonomous, task-oriented "AI agents" capable of working independently has long been the field’s north star. Yet despite considerable attention and effort, today's agents fall short of this vision.

What exactly is an AI agent, and how will agents change the way we work?

Internal software development is undergoing a quiet revolution. Generative AI is transforming the equation, collapsing the gap between idea and execution. Here’s how we got here, and why the next era of internal tooling is arriving sooner than expected.

Historically in vertical SaaS, companies were founded by domain experts who hired technical teams to build software for problems they had experienced firsthand. What we’re seeing now is the reverse. AI-native companies are largely led by technical founders, people who deeply understand large language models and what they can do. They’re not insiders to the industries they’re building in; they’re experts in the toolset.

We’re thrilled to be leading Sola’s Series A and joining their board. Sola is an AI-native process automation platform that allows business users to create, deploy, and maintain flexible, intelligent agents.

ChatGPT-5 just launched, marking a major milestone for OpenAI and the entire AI ecosystem.

What happens when a startup becomes a giant—and then has to reinvent itself all over again?

Permissioned data access appears to be under siege. If data access becomes a closed-loop system, what breaks — and what is lost?

Rillet is building the AI-native enterprise resource planning (ERP) system — a self-driving finance system designed from the ground up for speed, intelligence, and automation.

An AI-first workflow automation platform for lenders. The company builds AI agents to handle borrower interactions across voice, text, email, and chat.

In this episode, a16z General Partner Martin Casado sits down with Box cofounder and CEO Aaron Levie to talk about how AI is changing not just software, but the structure and speed of work itself.

Much of what worked for traditional SaaS companies doesn’t hold true for AI. Here's how enterprise AI startups are adapting, growing, and breaking out.

The AI-powered assistant operates discreetly on users' desktops, intelligently interpreting live audio and on-screen context to deliver proactive insights.

16 key shifts in how enterprises are budgeting for, buying, and deploying gen AI in 2025—and beyond.

New revenue benchmarks for gen AI startups in year one, based on dozens of enterprise and consumer AI companies we’ve spent significant time with.

Toma is a fully integrated, AI-powered software suite designed to help dealerships operate more efficiently.

Enterprises buying AI are like your grandma getting an iPhone: they want to use it, but they need you to set it up.

Market research has long relied on expensive human surveys. Now AI research companies are replacing them with simulated societies of generative AI agents.

Traditional search was built on links; GEO is built on language. A new paradigm is emerging, one driven not by page rank, but by AI models.

Business Process Outsourcing (BPO) is a $300 billion industry powering the back- and front-office operations of the world’s largest companies.

Younger founders often lack the deep networks important for distribution and earned insights around high-value problems that older founders have. AI changes that.

Camber is a company that is simplifying the healthcare reimbursement process for healthcare providers so they can focus on delivering quality care to their patients. 

Harvey's Aatish Nayak discusses building AI products for enterprises, including the legal profession, and how to address areas like UX, trust, and pricing.

The business process outsourcing (BPO) market is massive, and we believe there is a clear opportunity with AI to productize and unbundle the BPO.

Critical materials like copper, lithium, and gallium have been mined for decades, but their role in core technologies, geopolitics, and the energy transition have come to a height in recent years.

DeepSeek, China’s AI breakthrough, has exposed the U.S.'s policy failures. And not a day too soon.

Voice is one of the most powerful unlocks for AI application companies. As models improve, AI voice will become the wedge, not the product.

Intelligent automation is transforming industries by tackling messy, unstructured workflows that traditional Robotic Process Automation (RPA) couldn’t handle. In this episode, a16z partner Kimberly Tan discusses the shif...

Eve is the AI-native case workspace that acts as an intelligent partner for plaintiff attorneys, helping them take on 3-4x the number of cases that they were previously able to handle.

Decagon CEO Jesse Zhang and a16z's Kimberly Tan discuss how LLMs are reshaping customer support and how AI agents enable a disruptive pricing model.

In this episode of "My First 16," a16z Partner Seema Amble talks with MongoDB and Viam co-founder Eliot Horowitz about building sustainable open source software tools.

Did you know the U.S. nurse labor market is over $600 billion annually, but the dedicated software market for nurses is almost zero?

a16z Partner Seema Amble connects with Zapier co-founder Wade Foster about the company’s founding and GTM success utilizing a product-led growth (PLG) strategy.

In this episode of "My First Sixteen," a16z's Seema Amble chats with Gusto cofounder Tomer London about establishing product-market fit and product discovery.

An external "AI brain." Big swings in biopharma. Infinite games. A nuclear resurgence. "Faceless" creators. Google search challengers. Battlefield AI. We asked 50 a16z partners to preview one big idea that will spur innovation in 2025.

AI voice assistants for the freight industry. Customers are using Happyrobot for both inbound and outbound calls, including load updates, check calls, and carrier sales negotiations. 

In this post, we will look at how AI will open new markets previously deemed too “small” to support a large vertical SaaS company.

Sales is evolving. AI-native systems are replacing traditional CRM tools, capturing unstructured insights from emails, Slack, surveys, and more in real time. These systems automate early-stage tasks like prospecting and...

As AI turns labor into software, the opportunity to productize external professional services has become a hot topic. However, we believe there is also substantial opportunity in productizing internal work within organizations.